AVP Crystals

A. Introduction

AVP Crystals are a premium laboratory‑grade neuropeptide research compound provided as a lyophilized or highly crystalline solid form of arginine vasopressin (AVP), a cyclic nonapeptide hormone historically studied for its signaling role at vasopressin receptor subtypes. The crystalline format offers researchers a stable, contamination‑minimized peptide material suitable for high‑precision gravimetric dispensing, molecular‑biology buffer reconstitution, and longitudinal stability‑study work in controlled, non‑clinical environments. The product is supplied strictly for analytical and biochemical research and is not intended for any human or animal‑facing application.

B. Scientific Overview

Arginine vasopressin (AVP, CAS 113‑79‑1) is a cyclic nonapeptide hormone that mediates its effects through three principal G protein–coupled receptor (GPCR) subtypes—V1a, V1b, and V2—along with partial cross‑activation of the oxytocin receptor in some systems. Within the scientific literature, AVP‑crystal or AVP‑peptide preparations are primarily used as reference hormones for receptor‑ligand binding assays, hormone‑receptor crystallography, cryo‑EM structural studies, and signal‑transduction‑pathway characterization under strictly controlled in‑vitro research conditions. AVP Crystals are supplied as a laboratory‑grade neuropeptide reference material and must not be used for diagnostic, therapeutic, or consumer‑oriented purposes.

C. Product Specifications

• Product Name: AVP Crystals

• Chemical Name: Arginine Vasopressin (AVP), cyclic nonapeptide

• Synonym: Arg8‑vasopressin, antidiuretic hormone, ADH

• CAS Number: 113‑79‑1

• Molecular Formula: C₄₆H₆₅N₁₅O₁₂S₂ (freebase, common cyclic form)

• Molecular Weight: Approximately 1084.21 g/mol

• Form: Lyophilized or crystalline solid (freeze‑dried vial or crystalline powder)

• Purity: Typically ≥ 97–99% peptide‑grade by HPLC, with low residual solvent and peptide‑related by‑products

• Appearance: White to off‑white crystalline solid or lyophilized cake

• Solubility: Generally soluble in water and mild aqueous buffers (e.g., PBS, Tris), with typical working‑stock solutions ranging from nanomolar to micromolar concentrations for receptor‑binding and cell‑based assays

• Storage Conditions: Store lyophilized or crystalline AVP at ≤ −20°C, protected from light and moisture, preferably under inert gas in sealed vials to minimize oxidation and degradation

D. Laboratory Use Context

AVP Crystals are positioned exclusively for in‑vitro, analytical, and non‑clinical research, including GPCR‑ligand binding and activation studies at vasopressin V1a, V1b, and V2 receptor subtypes, structural‑biology work such as cryo‑EM and X‑ray crystallography of AVP‑receptor complexes, and cell‑based signaling‑pathway assays involving Gq/Gs‑coupled second‑messenger systems. The crystalline or lyophilized format supports precise reconstitution into defined‑volume buffer stocks, freeze‑thaw‑cycle‑minimized aliquoting, and long‑term stability‑testing protocols, making it particularly useful for endocrinology, molecular‑pharmacology, and peptidology laboratories. This product must not be used in any human or animal‑focused therapeutic, preventive, or diagnostic context and is reserved strictly for lawfully authorized, laboratory‑based research conducted by qualified personnel.

E. Quality & Testing

Every batch of AVP Crystals undergoes rigorous quality assurance:

• Third‑party Certificate of Analysis (COA) available upon request, including HPLC purity, mass‑spectrometry‑based identity confirmation, and endotoxin or bioburden limits where applicable

• Batch‑specific tracking and full documentation for chain‑of‑custody and traceability in regulated research environments

• Independent verification of peptide sequence integrity, disulfide‑bond formation, and common impurities such as deamidated or truncated forms, with typical impurity profiles kept below established thresholds

• Manufactured under controlled, ISO‑ or GMP‑aligned peptide‑production conditions to ensure consistent batch‑to‑batch reproducibility, accurate mass content, and suitable secondary‑structure integrity for receptor‑binding and structural‑biology studies

F. Shipping & Handling

We provide discreet, professional shipping worldwide to qualified research institutions and laboratories. AVP Crystals are securely packaged in temperature‑controlled, light‑resistant vials within secondary desiccated containers, often shipped with cold‑chain materials if lyophilized, to help maintain peptide integrity during transit. Tracking information is supplied with every shipment, and packaging is designed to minimize exposure to temperature excursions, humidity, and physical shocks. Researchers are responsible for verifying the legality of importation and handling in their jurisdiction prior to ordering, including compliance with local regulations governing peptide hormones and research‑grade peptides.

G. Compliance Disclaimer

For Research Use Only. Not for human consumption.
This product is sold strictly for laboratory and analytical research purposes. It is not intended for human or veterinary use, ingestion, or any form of consumption. No claims are made regarding effects on biological systems outside of controlled in‑vitro research settings.

Buyers must be qualified researchers or institutions and agree to comply with all local, state, federal, and international regulations governing peptide hormones and research‑grade peptides. The seller assumes no liability for misuse. Always consult your institution’s safety and compliance guidelines before receiving, storing, or handling AVP Crystals.